- Leptospirosis is an infectious disease that can occur in humans and animals worldwide.
- A spirochete, Leptospira interrogans, causes leptospirosis.
- High risk factors include close association with animals and the water and soil they may contaminate with infected urine.
- Symptoms and signs of leptospirosis are highly variable and range from no symptoms to nonspecific symptoms including high fever, chills,headache, abdominal symptoms to Weil's disease with organ dysfunction.
- Definitive diagnosis is done by isolating the bacteria from the patient serological tests are also available.
- There are antibiotics that are effective in treating leptospirosis.
- Most people infected with Leptospira interrogans bacteria have a good prognosis a few have a more guarded prognosis.
- Vaccines are available for humans and animals in some countries there is no vaccine available commercially for humans in the U.S. available vaccines are very limited because they usually only protect well against a single serovar. Doxycycline (Vibramycin, Oracea, Adoxa, Atridox) has been used as a short-term prophylactic treatment to protect some humans from leptospirosis.
What is leptospirosis
Leptospirosis is a disease caused by bacteria (Leptospira interrogans) that produce a wide range of symptoms that may occur in phases some patients may develop kidney or liver failure, respiratory failure, meningitis, or even death. The disease is spread by the urine of infected animals (many species, both domesticated and wild) the bacteria can survive in the water and soil for months. The disease is most common in temperate and tropical climates. The infecting bacteria occur worldwide.