Appendicitis (also called epityphlitis) is inflammation of the appendix and is a surgical emergency. Many cases of appendicitis require removal of the inflamed appendix by laparotomy or laparoscopy due to the high mortality associated with rupture of the appendix, which may lead to severe complications such as

  • peritonitis and
  • sepsis.

Appendicitis was first described by Reginald Fitzin 1886, and is today recognized as one of the most common and significant causes of severe acute abdominal pain worldwide.